Several risk factors are associated with an increased chance of developing hereditary hemochromatosis:

Hemochromatosis is treated by removing excess iron from the body to bring iron levels back down to normal.

People affected with hemochromatosis begin accumulating iron from a young age but the symptoms do not appear until later in life.

Hemochromatosis is a common disease but it is often misdiagnosed or an accurate diagnosis is delayed. This delay leads to an excessive build up of

Hemochromatosis DNA testing identifies the presence or absence of three mutations in the HFEgene – C282Y (c.845G>A), H63D (c.187C>G) and S65C (c.193A>T).

The HFE gene encodes an HLA class I-like protein that is displayed on the cell surface as part of a heterodimer with β-2 microglobulin.

Hereditary hemochromatosis is an autosomal recessive genetic disorder that affects iron metabolism. Over 85% of patients with hereditary hemochromatosis have detectable mutations in the HFE gene.

Hemochromatosis is an iron disorder in which the body absorbs and stores too much iron. There are two types of hemochromatosis – primary and secondary.

Hereditary or primary hemochromatosis is caused by defects in the HFE gene. One of the roles of the HFE protein is to regulate the amount of iron